异麦芽低聚糖对肠道菌群的调节作用

本研究观察了异麦芽低聚糖对肠道菌群的调节作用。动物实验 :BABL C小鼠 40只 ,随机分为 3个剂量组 (低、中、高 )和 1个对照组 ,每组 1 0只。每组动物经口给与相应剂量的异麦芽低聚糖 ,对照组给水 ,7天后留取各组小鼠粪便分析肠道菌群。人体实验 :30名健康成人 (女 1 5人 ,男 1 5人 ) ,每天服用 30g含异麦芽低聚糖的产品 (相当于 1 5g异麦芽低聚糖 ) ,7天后留取粪便进行肠道菌群分析 ,结果表明 :异麦芽低聚糖对BALB c小鼠和受试人群的肠道菌群均具有一定的调节作用 ;对小鼠和人肠道的双歧杆菌、人肠道中的乳杆菌具有增殖作用 ,并具有抑制人肠道产气荚膜梭菌生长的作用

Study on the regulative effect of isomaltooligosaccharides on human intestinal flora

Objective In order to study the effect of Isomaltooligosaccharides on Human and mouse intestinal flora in vivo. Methods 1. 30 health subjects (15 male, 15 female) were randomly selected from the clinic of Tianjin CDC. They were provide 15 g Isomaltooligosaccharides once a day for 7 days; 2. 40 BABL/c mice were divided into 4 groups, 3 experimental groups and 1 control group. These 3 experimental groups were fed different dose of Isomaltooligosaccharides by gavage for 7 days. Feces of both human and mice were determined before and at the end of the experiment. Results The results showed that the reproduction of Bifidobacteria and Lactobacillus greatly increased, and the growth of Clostridium perfriengenes was significantly inhibited both in mice and human intestinal tracts. Conclusion Isomaltooligosaccharides could regulate and improve the intestinal flora in both mice and human intestine.