| 肺癌患者的血浆、胸水纤溶活性及其临床意义 |
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| 引用本文： | 谢敏,李少娅,任敏,王曾礼.肺癌患者的血浆、胸水纤溶活性及其临床意义[J].四川医学,2001,22(11):1027-1028. |
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| 作者姓名： | 谢敏 李少娅 任敏 王曾礼 |
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| 作者单位： | 1. 华西医科大学附属第一医院
2. 云南省保山地区人民医院 |
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| 摘 要： | 目的：研究纤溶活性在肺癌扩散中的影响。方法：检测29例肺癌患者、21例良性胸腔积液患者血浆、胸液中组织纤溶酶原激活物活性（t－PA）纤溶酶原活化抑制因子（PAI－1）活性。结果：肺癌组血浆、胸液中（t－PA)活性均明显高于对照组（P＜0．05），而PAI－1活性则与对照组相似（P＞0．05）。结论：肺癌患者的纤溶失衡与其远处转移可能有一定关系。
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| 关 键 词： | 肺肿瘤 胸水 血浆 纤溶性 |
| 文章编号： | 1004-0501(2001)11-1027-02 |
| 修稿时间： | 2001年2月11日 |
Fibrinolytic activity in plasma and pleural fluid of patients with lung cancer. |
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| Xie Min ,Li Shanya ,Ren Min ,et al..Fibrinolytic activity in plasma and pleural fluid of patients with lung cancer.[J].Sichuan Medical Journal,2001,22(11):1027-1028. |
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| Authors: | Xie Min Li Shanya Ren Min |
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| Institution: | Xie Min 1,Li Shanya 2,Ren Min 1,et al. The First Affiliated Hospital West China University of Medical Sciences,Chengdu,Sichuan 610041 |
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| Abstract: | Objective To measure and evaluate the effects of fibrinolytic activity on distant metastasis in lung cancer.Methods In this study tissue type plasminogen activator(t PA) and plasminogen activator inhibitor 1(PAI 1)activity were measured in the plasma and pleural fluid samples from 29 patients with lung cancer and 21 patients with benign hydrothorax.Results In comparison with the benign hydrothorax group,the lung cancer group had significantly higher level of t PA activity in plasma and pleural fluid( P <0 05),but no significant difference in PAI 1 activity was observed between the two groups( P> 0 05).Conclusion The umbalanced fibrinolytic system is probably responsible for the distant metastasis in lung cancer. |
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| Keywords: | Lung tumour Fibrinolysis Pleural fluid |
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