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结直肠癌同时肝转移和腹膜转移的处理及预后
引用本文:宋武,何裕隆,蔡世荣,张常华,陈创奇,詹文华.结直肠癌同时肝转移和腹膜转移的处理及预后[J].中国普通外科杂志,2008,17(10):2-954.
作者姓名:宋武  何裕隆  蔡世荣  张常华  陈创奇  詹文华
作者单位:中山大学附属第一医院胃肠胰外科、中山大学胃癌诊治中心,广东广州510080
摘    要:目的 探讨结直肠癌同时性肝转移和腹膜扩散患者的相关临床病理因素以及手术干预对其预后的影响.方法 回顾性分析12年间中山大学附属第一医院肠癌数据库资料中有同时性肝转移和/或腹膜扩散患者(166例/150例)的临床病例资料及随访结果.结果 在诸多病理因素中肿瘤分化程度和浆膜浸润与腹膜扩散有关(P<0.01),而肿瘤分化程度,浆膜浸润和Ducks分期等与同时性肝转移有关(P<0.01);手术不可切除的结直肠癌伴同时性肝转移组与伴腹膜扩散组的短期和长期生存率差异无统计学意义(P>0.05),而在手术可切除组中伴腹膜扩散者的长期生存率优于伴肝转移者(P<0.01).结论 结直肠癌腹膜转移患者较同时性肝转移患者长期顶后好;手术不可切除的结直肠癌伴腹膜扩散或肝转移才标示着肿瘤的终末期;结直肠癌伴腹膜转移根治切除组较伴同时性肝转移根治切除组预后好,局限的结直肠癌伴腹膜转移通过手术可能得到根治.

关 键 词:结直肠肿瘤/外科学  肝肿瘤/继发性  腹膜扩散  肿瘤转移  预后
收稿时间:1900/1/1 0:00:00
修稿时间:1900/1/1 0:00:00

Treatment and prognosis of synchronous hepatic metastasis and peritoneal dissemination in colorectal cancer
SONG Wu,HE Yulong,CAI Shirong,ZHANG Changhu,CHEN Chuangqi,ZHAN Wenhua.Treatment and prognosis of synchronous hepatic metastasis and peritoneal dissemination in colorectal cancer[J].Chinese Journal of General Surgery,2008,17(10):2-954.
Authors:SONG Wu  HE Yulong  CAI Shirong  ZHANG Changhu  CHEN Chuangqi  ZHAN Wenhua
Institution:SONG Wu,HE Yulong,CAI Shirong,ZHANG Changhua,CHEN Chuangqi,ZHAN Wenhua(Department of Gastrointestinal , Pancreatic Surgery,the First Affiliated Hospital,Sun Yet-san University,Gastric Cancer Diagnosis , Therapeutic Center,Zhongshan University,Guangzhou 510080,China)
Abstract:Objective To investigate the correlation of pathologic factors with the prognosis of colorectal cancer patients with peritoneal dissemination and/or synchronous liver metastasis,and the effect of surgical intervention on the prognosis.Methods Based on our 12-year database,the clinicopathologic data and the result of follow-up of colorectal cancer complicated with peritoneal dissemination(150 cases) and/or synchronous liver metastasis(166 cases) were analyzed retrospectively.Results Multi-variate analysis in...
Keywords:Colorectal Neoplasms/surg  Liver Neoplasms /second  Peritoneal Dissemination  Neoplasm Metastasis  Prognosis  
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