261株呼吸道致病菌的耐药性分析

目的：了解本院近期呼吸道致病菌的耐药状况。方法：应用K-B纸片法测定了1998年10月至2000年5月从临床标本中分离出的261株呼吸道致病菌对31种抗菌药的耐药率。结果：耐药率结果如下：铜绿假单胞菌对青雷家、吡哌酸为90％；不动杆菌对庆大素和妥布霉素分别为68％、86％，对三代头脑菌素为30％以上；嗜麦芽假单胞菌对三代头脑菌素也在49．0％以上、依诺沙星80．8％。结论：定期、系统的耐药性监测对临床合理有效地使用抗菌药有重要的指导意义。

Analysis of antibiotic-resistance of 261 bacterial strains isolated from patients with respiratory infections

Objective:To know antibiotic-resistance in patients with respiratory infections. Methods: The resistance rate of 261 strains isolated from patients with respiratory infections to 31 antibacterial agents were examined with K-B method from Oct. 1998 to May 2000. Results: The results showed that the resistant rate of Pseudomonas aeruginosa to penicillin and pipemidic acid was 90%; Acinetobacter to the third Cefo was over 30% and to gentamycin and tobramycin were 68% and 86%, respectively. The resistance rates of Pseudomonas maltophilia to the third Cefo and enoxacin were over 40% and 80%, respectively. Conclusion: Periodical examination of resistance rates of bacteria has important significance to clinical drug use.