| 便秘的肛门直肠动力和血浆活性肠肽变化的研究 |
| |
| 引用本文： | 张义侠,林红,刘峥艳,傅宝玉.便秘的肛门直肠动力和血浆活性肠肽变化的研究[J].中国医科大学学报,2006,35(2):183-184. |
| |
| 作者姓名： | 张义侠 林红 刘峥艳 傅宝玉 |
| |
| 作者单位： | 中国医科大学附属第一医院消化内科,辽宁,沈阳,110001 |
| |
| 摘 要： | 目的：观察慢性便秘各型的肛门直肠动力学和感觉功能的变化，测定血浆中血管活性肠肽（VIP）的变化。方法：用肛门直肠测压的方法测定直肠肛门动力及感觉功能；用放免法检测血浆中VIP的含量。结果：传输时阔正常型便秘蛆的肛管静息压降低（P〈0．05）；传输时间延长型便秘组肛管静息压降低。直肠最大耐受容积增大（P〈0．05）；便秘各型血浆中VIP均升高（P〈0．05）。结论：不同类型的便秘存在不同的结肠、肛门直肠动力学改变和内脏感觉异常。血策VIP水平升高在慢性便秘的发病机制中可能起作用。
|
| 关 键 词： | 便秘 结肠传输时间 肛门直肠动力 血管活性肠肽 |
| 文章编号： | 0258-4646(2006)02-0183-02 |
| 收稿时间： | 2004-09-12 |
| 修稿时间： | 2004年9月2日 |
Changes of anorectal motility and serum vasoactive intestinal polypeptide in patients with chronic constipation |
| |
| ZHANG Yi-xia,LIN Hong,LIU Zheng-yan,FU Bao-yu.Changes of anorectal motility and serum vasoactive intestinal polypeptide in patients with chronic constipation[J].Journal of China Medical University,2006,35(2):183-184. |
| |
| Authors: | ZHANG Yi-xia LIN Hong LIU Zheng-yan FU Bao-yu |
| |
| Institution: | Department of Gastroenterology, The First Affiliated Hospital, China Medical University, Shenyang 110001, China |
| |
| Abstract: | Objective: To investigated the changes of anorectal motility and sensory function in patients with different types of chronic constipation.Methods:Anorectal manometry was performed to determine the changes of anorectal motility and sensory function.The content of serum vasoactive intestinal peptide(VIP) was detected.Results:The anal resting pressure in patients with normal and delayed transit time was significantly lower than that in normal controls(P<0.05).The rectal maximum tolerable volume in patients with delayed transit time was significantly larger than that in normal controls(P<0.05).The serum VIP in each type of chronic constipation was significantly higher than that in normal controls(P<0.05).Conclusion:The anarectal motility and rectal sensation vary in different types of chronic constipation.The elevated level of serum VIP may be involved in the pathogenesis of chronic constipation. |
| |
| Keywords: | chronic constipation colonic transit time anorectal motility vasoactive intestinal polypeptide |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
