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注射用硫酸头孢匹罗与4种不同输液的稳定性考察
引用本文:陈芳,顾雪英.注射用硫酸头孢匹罗与4种不同输液的稳定性考察[J].抗感染药学,2008,5(2):79-82.
作者姓名:陈芳  顾雪英
作者单位:苏州市立医院东区,江苏,苏州,215001
摘    要:目的:考察注射用硫酸头孢匹罗与葡萄糖注射液、氯化钠注射液、复方氯化钠注射液及木糖醇注射液配伍后的稳定性。方法:采用高效液相色谱法考察注射用硫酸头孢匹罗在葡萄糖注射液、氯化钠注射液、复方氯化钠注射液及木糖醇注射液中配伍后8h内含量、颜色与pH值的变化。结果:在室温条件下,各配伍溶液外观性状、pH值及含量无明显变化。结论:注射用硫酸头孢匹罗可以与葡萄糖注射液、氯化钠注射液、复方氯化钠注射液及木糖醇注射液配伍。

关 键 词:硫酸头孢匹罗  高效液相色谱法  稳定性

Stability Study of Cefpirome Sulfate for Injection in 4 Kinds of Different Infusions
CHEN Fang East Area,Municipal Hospital of Suzhou,Suzhou Jiangsu ,China.Stability Study of Cefpirome Sulfate for Injection in 4 Kinds of Different Infusions[J].Anti-infection Pharmacy,2008,5(2):79-82.
Authors:CHEN Fang East Area  Municipal Hospital of Suzhou  Suzhou Jiangsu  China
Institution:CHEN Fang~* East Area,Municipal Hospital of Suzhou,Suzhou Jiangsu 215001,China
Abstract:Objective: To study the stability of compatibility between cefpirome sulfate for injection and glucose, sodium chloride, compound chloride and xylitol infusions. Methods: To abserve solution appearance, pH values, cefpirome sulfate level etc., After compatibilities testing ofcefpirome sulfate for Injection with glucose, sodium chloride, compound chloride and xylitol infusions. Results: Within 0-8 h at room temperature, the appearance, pH and its content have no obvious changes. Conlusion: Cefpirome sulfate for injection when mixed with four kinds of infusion is basically stable.
Keywords:cefpirome sulfate  HPLC  stability
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