心肌酶谱与肌钙蛋白Ⅰ测定在急性心肌梗死早期诊断中的临床价值

目的:探讨心肌酶谱和肌钙蛋白Ⅰ(cTnI)测定在急性心肌梗死(AMI)早期诊断中的临床应用价值.方法:采用日立7600-020全自动生化分析仪及诊断试剂盒,检测了87例AMI患者心肌酶谱(AST、LDH、CK.、CK-MB)和cTnI,并比较其特异性和敏感性.结果:87例AMI患者血清cTnI、CK、CK-MB、AST、LDH水平与正常对照组比较差异均有非常显著性(P＜0.01),87例AMI患者中,75例心肌酶谱升高,82例肌钙蛋白Ⅰ阳性,敏感性分别为86.2%、94.3%;特异性分别为92.0%、96.0%.结论:心肌酶谱与cTnI测定在AMI早期诊断中具有重要的临床价值.

Clinical value of early diagnosis of myocardial enzymes and cTnI determination in acute myocardial infarction

Objective:To investigate the clinical value of myocardial enzymes and troponin I(cTnI) measurement in the diagnosis of acute myocardial infarction(AMI).Methods:Hitachi 7600-020 automatic biochemical analyzer and diagnostic kits were used to detect myocardial enzymes(AST,LDH,CK,CK-MB) and cTnI in 87 cases of AMI for comparing their specificity and sensitivity.Results:cTnI,CK,CK-MB,AST,LDH levels in 87 cases of AMI had significant difference compared with the control group(P<0.01).Among 87 cases,myocardial en...