他巴唑与131I治疗甲亢的临床疗效对比分析

目的 探究他巴唑和131I在治疗甲状腺功能亢进中的临床效果. 方法 整群选取2013年9月—2015年1月该院收治的65例甲状腺功能亢进患者为研究对象,将其随机划分为对照组和观察组,对照组32例患者,治疗组33例患者,对照组采用他巴唑进行治疗,观察组采用131I进行治疗,对两组治疗效果进行比较分析. 结果 观察组患者中显效人数27例,治疗总有效率为81.8%,对照组患者中显效人数22例,治疗总有效率为68.8%,观察组的治疗效果明显优于对照组,差异有统计学意义(P<0.05).观察组甲低并发率为6.1%,治愈后的并发率为3%,对照组的甲低并发率为25%,治愈后的并发率为12.5%,观察组的各项不良反应发生几率明显低于对照组,差异有统计学意义(P<0.05).结论 对甲状腺功能亢进患者采用131I进行治疗其效果比较明显,具有安全性高和不良反应少的特点,值得临床推广和应用.

Clinical Curative Effect Comparison of Methimazole and 131I in the Treat-ment of Hyperthyreosis

Objective To study the clinical effect of methimazole and 131I in the treatment of hyperthyreosis. Methods 65 cases of patients with hyperthyreosis treated in our hospital from September 2013 to January 2015 were selected as the re-search object and randomly divided into control group (n=32) and observation group (n=33), the control group were treated with methimazole, the observation group were treated with 131I, the treatment effects of the two groups were compared and analyzed. Results In the observation group, the effective number was 27 cases and the total effective rate of treatment was 81.8%, in the control group, the effective number was 22 cases and the total effective rate of treatment was 68.8%, the treatment effect in the observation group was obviously better than that in the control group, and the difference was obvi-ously different (P<0.05), in the observation group, the hypothyroidism coincidence was 6.1% and the coincidence after cured was 3%, in the control group, the hypothyroidism coincidence was 25%and the coincidence after cured was 12.5%, the incidence of all kinds of adverse reaction in the observation group was obviously lower than that in the control group, and the difference was obvious (P<0.05). Conclusion 131I treatment for patients with hyperthyreosis has an obvious effect and has the characters of high security and few adverse reaction, which is worthy of promotion and application in clinic.