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脑胶质瘤立体定向靶向微创手术临床应用分析
引用本文:段国庆,陈小兵,胡文忠.脑胶质瘤立体定向靶向微创手术临床应用分析[J].中外医疗,2016(2).
作者姓名:段国庆  陈小兵  胡文忠
作者单位:河南大学淮河医院神经外科,河南开封,475000
摘    要:目的 研究分析脑胶质瘤立体定向靶向微创手术的临床治疗效果. 方法 随机选取该院2012年6月—2014年10月收治的胶质瘤患者70例,随机分为对照组和观察组各35例,给予对照组常规开颅肿瘤切除术治疗,观察组采取胶质瘤立体定向靶向微创手术治疗,观察两组患者的治疗效果. 结果 所有患者通过治疗之后,观察组患者的2年存活率为88.6%,复发率为14.3%,对照组患者的2年存活率为71.4%,复发率为40.0%,观察组的存活率与复发率明显优于对照组,差异有统计学意义(P<0.05). 另外,观察组的ADL评分以及神经功能评分均明显优于对照组,差异有统计学意义(P<0.05). 结论 通过使用立体定向靶向微创手术治疗胶质瘤,可以取得较好的治疗效果,其操作简便,创伤较小,费用较低,具有较高的临床应用价值.

关 键 词:脑胶质瘤  立体定向靶向微创手术  临床应用

Clinical Analysis of the Effect of Stereotactic Targeting Minimally Invasive Surgery in the Treatment of Brain Glioma
Abstract:Objective To analyze the clinical effect of stereotactic targeting minimally invasive surgery in the treatment of brain glioma. Methods 70 patients with brain glioma admitted in our hospital from June 2012 to October 2014 were select-ed and randomly divided into control group and observation group with 35 cases in each. The control group were treated by the conventional tumor resection by craniotomy. The observation group were treated by stereotactic targeting minimally inva-sive surgery. And the treatment effect of the two groups was observed. Results After treatment, compared with the control group, the observation group had higher 2-year survival rate(88.6% vs 71.4%) and lower recurrence rate(14.3% vs 40.0%) with statistically significant differences (P<0.05). In addition, the ADL scores and nerve function score in the observation group were significantly better than those in the control group with statistically significant differences (P<0.05). Conclusion For the treatment of brain glioma, stereotactic targeting minimally invasive surgery is easy to operate with minimal invasion, low cost, good effect and high clinical application value.
Keywords:Brain glioma  Stereotactic targeting minimally invasive surgery  Clinical application
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