充血性心力衰竭患者左室纵向心肌运动速度与射血分数的相关性

目的探讨充血性心力衰竭（HF）患者中组织多普勒显像（TDI）获得的左室纵向室壁运动速度与左室射血分数（EF）之间的相关关系，评价左室纵向室壁运动速度识别HF的价值。方法81例HF患者，30例正常对照者纳入本研究。应用改良Simpson法测量左室EF。根据EF将HF分为收缩性HF组（EF〈50％，n=29）和舒张性HF组（EF≥50％，n=52）。于二尖瓣环6个位点测量左室纵向收缩期峰值速度Sm、舒张早期峰值速度Em和舒张晚期峰值速度Am。结果收缩性HF组Sm、Em、Am明显低于对照组（P〈0．001）；舒张性HF组Em、Era／Am明显低于对照组（均P〈0．001）。Sm、Em、Am、E／Em与EF之间呈线性相关（分别为r=0．68，r=0．38，r=0．53，r=-0．55，P〈0．001）。Sm、Em、Atn预测EF的ROC曲线下面积分别为0．921、0．784和0．825。结论不论EF如何，HF患者均不同程度存在舒张功能障碍，TDI获得的左室纵向室壁运动速度与左室射血分数之间的相关关系良好，收缩期峰值速度Sm能有力地预测心力衰竭。

Correlation Between Left Ventricular Longitudinal Wall Motion Velocity and LVEF in Patients With Chronic Heart Failure

Objective To investigate the correlation between left ventricular longitudinal wall motion velocity obtained from the tissue Doppler imaging(TDI) and left ventricular ejection fraction(EF) in patients with chronic heart failure(HF),and to evaluate the power of indentifying patients with heart failure by left ventricular longitudinal wall motion velocity. Methods Eighty-one patients with HF and 30 controls were included.Left ventricular EF was measured by modified Simpson's method.HF has been classified as s...