| 齐拉西酮与利培酮治疗首发精神分裂症对照研究 |
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| 引用本文： | 奈效祯,史丽,宋春联,赵绍锋. 齐拉西酮与利培酮治疗首发精神分裂症对照研究[J]. 河南职工医学院学报, 2008, 20(3): 226-228 |
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| 作者姓名： | 奈效祯 史丽 宋春联 赵绍锋 |
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| 作者单位： | 郑州市第八人民医院精神科,河南,郑州,450006 |
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| 摘 要： | 目的比较齐拉西酮与利培酮对首发精神分裂症的疗效及安全性。方法将70例首发精神分裂症患者随机分为齐拉西酮组36例，利培酮组34例，分别给予齐拉西酮和利培酮治疗，疗程8周。在治疗前及治疗1、2、4、6、8周末分别采用阳性与阴性量表（PANSS）、治疗中出现的症状量表（TESS）对2组进行评定。结果2组治疗后PANSS评分均有显著下降。齐拉两酮组体质量增加及月经失调均较利培酮少而轻。结论2种药对首发精神分裂症均有较好的疗效，不良反应小。
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| 关 键 词： | 齐拉西酮 利培酮 首发精神分裂症 |
| 文章编号： | 1008-9276(2008)03-0226-03 |
| 修稿时间： | 2007-11-20 |
Comparative Study on Ziprasidone and Risperidone in Treating First Episode Schizophrenia |
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| NAI Xiao-zhen,SHI Li,SONG Chun-lian,ZHAO Shao-feng. Comparative Study on Ziprasidone and Risperidone in Treating First Episode Schizophrenia[J]. Journal of Henan Medical College For Staff and Workers, 2008, 20(3): 226-228 |
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| Authors: | NAI Xiao-zhen SHI Li SONG Chun-lian ZHAO Shao-feng |
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| Affiliation: | NAI Xiao-zhen,SHI Li,SONG Chun-lian,ZHAO Shao-feng(Psychiatric Department of the Eighth People's Hospital,Zhengzhou Henan 450006,China) |
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| Abstract: | Objective To compare the efficiency and safety of ziprasidone and risperidone in the treatment of first episode schizophrenia.Methods 70 patients with first episode schizophrenia were randomly divided into ziprasidone group(n=36) and risperidone group(n=34) for 8 treatment weeks.Positive and negative syndrome scale(PANSS) emergent symptoms scale(TESS) were evaluated before and after 1,2,4,6,8 treatment week for both groups.Results The total scores of PANSS reduced significantly after treatment in both group... |
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| Keywords: | zipradone risperidone first episode schizophrenia |
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