脑梗死患者早期应用氟西汀对卒中后康复影响的观察

目的评价氟西汀早期应用脑梗死患者对患者康复的影响。方法随机将符合诊断标准的40例脑梗死的患者分为治疗组和对照组各20例进行治疗观察。治疗组早期给予氟西汀,2组其他常规治疗药物相同。结果治疗4周后治疗组在神经功能缺损评分及日常生活活动能力Barthel指数均优于对照组,差异有统计学意义(P<0.05和P<0.01)。结论早期预防性应用氟西汀可使脑梗死患者卒中后抑郁发生及相关症状明显缓解,更利于调整患者的情绪,使患者积极参与康复训练以利康复。

Effect observation of early application of fluoxetine in the treatment of post-stroke rehabilitation in patients with cerebral infarction

Objective To evaluate the effect of early application of fluoxetine in the treatment of post-stroke rehabilitation in patients with cerebral infarction.Methods 40 patients with cerebral infarction were randomly divided into treatment group and control group,each of 20 cases.The treatment group was given fluoxetine for treatment,and the other conventional drugs of 2 groups were the same.Results 4 weeks after treatment,the neurological deficit score and Barthel index of activities of daily living of the treatment group were better than those of the control group,and the differences were statistically significant （P0.05）.Conclusion The early application of fluoxetine can relieve post-stroke depression and related symptoms of patients with cerebral infarction obviously,be more in favor of adjusting the emotions of patients and make patients participate in rehabilitation training actively.