| γ射线辐照和保存期对血小板的影响 |
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| 引用本文： | 王明元,张友九,周晓华,王春雷,程根林,李丽,万建美,方振羊. γ射线辐照和保存期对血小板的影响[J]. 齐齐哈尔医学院学报, 2006, 27(9): 1028-1029 |
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| 作者姓名： | 王明元 张友九 周晓华 王春雷 程根林 李丽 万建美 方振羊 |
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| 作者单位： | 苏州市红十字中心血站,215006;苏州大学放射医学与公共卫生学院,215006 |
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| 基金项目： | 江苏省卫生厅医学科技发展基金资助项目（No：H200341）;苏州市社会发展科技计划资助项目（No：SS0416）. |
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| 摘 要： | 目的了解γ射线辐照和保存期对单采血小板的影响。方法单采血小板分为两组:一组25Gy剂量辐照,一组不辐照处理,作为对照组;在贮存的第0、5天分别检测单采血小板计数、pH和表达CD62P的特异性荧光结合阳性血小板百分率(%)。结果保存过程中,辐照组血小板计数及pH值与对照组无显著差异(P>0.05);5天的贮存可显著增加了血小板表达CD62P百分率(P<0.05),但辐照组与对照组的血小板在贮存第5天时表达CD62P百分率无显著差异(P>0.05)。结论25Gy的辐照对血小板制品的质量无明显影响,与普通血小板制品相同,辐照单采血小板可保存5天。
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| 关 键 词： | 血小板 辐照 CD62P |
| 收稿时间： | 2006-02-07 |
| 修稿时间： | 2006-02-07 |
Influence of Gamma Irradiation and Storage on Apheresis Platelets |
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| Wang Mingyuan ,et al.. Influence of Gamma Irradiation and Storage on Apheresis Platelets[J]. Journal of Qiqihar Medical College, 2006, 27(9): 1028-1029 |
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| Authors: | Wang Mingyuan et al. |
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| Affiliation: | Suzhou Red Cross Blood Center,Suzhou,Jiangsu 215006 |
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| Abstract: | Objective To investigate the influence of irradiation and storage on apheresis platelets.Methods Apheresis platelets were divided into two groups: one was irradiated with 25Gy,and the other served as a control.Platelet counts,pH and platelet activation marker CD62 antigen were determined in paired samples on the day of collection (day 0) and after 5 days of storage (day 5).Results No significant differences in Platelet counts and PH between the irradiated and control platelets on day 0 or day 5.The 5-day storage significantly increased the percentages of CD62 percentages of CD62_P staining was no significant differences in irradiated and control platelets on day 5(P>0.05).Conclusions Irradiation of 25Gy has not obviously influenced on the quality of apheresis platelets.The irradiated apheresis platelets can be kept for 5 days as ordinary apheresis platelets. |
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| Keywords: | Blood Platelets Irradiation CD62_P |
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