| 头孢硫咪体外抗菌活性测定 |
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| 引用本文： | 唐英春,张扣兴,等.头孢硫咪体外抗菌活性测定[J].中国药师,2001,4(1):46-48. |
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| 作者姓名： | 唐英春 张扣兴 |
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| 作者单位： | 中山医科大学附属三院呼吸内科,广州,510630 |
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| 摘 要： | 目的：评价第一代头孢菌素头孢硫脒对近期从临床分离的致病菌的体外抗菌活性。方法：用对倍稀释法测定头孢硫咪的最小抑菌浓度（ＭＩＣ）并与头孢唑啉、头孢呋辛、头孢他啶体外抗菌活性进行了对比。结果：头孢硫脒对肺炎球菌、化脓性链球菌、ＭＳＳＡ、ＭＳＳＥ和卡他布汉氏菌有较强的抗菌活性。结论：头孢硫脒对Ｇ^＋球菌有较强的抑菌活性和杀菌活性，对肠球菌亦显示有很强的体外抗菌活性。
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| 关 键 词： | 头孢硫脒 最低抑菌浓度 最低杀菌浓度 体外抗菌 |
| 修稿时间： | 2000年6月21日 |
Determination of Activity in vitro of Cefathiamidine Against Bacteria |
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| Tang Yingchun,Zhang Kouxing,Wu benquan,Zhang Tiantuo,Tan Shucing.Determination of Activity in vitro of Cefathiamidine Against Bacteria[J].China Pharmacist,2001,4(1):46-48. |
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| Authors: | Tang Yingchun Zhang Kouxing Wu benquan Zhang Tiantuo Tan Shuc]ing |
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| Abstract: | Objective: To evaluate the activity in vitro of the first generation cephalosporin cefathiamidine on the bacteria isolated from recent clinic. Methods: Minimal inhibitory concentrations ( MICs) of cefathiamidine were determined by standard agar dilution method and compared with the MICs of cefazolin, cefuroxime and ceftazidime. Results: Cefathiamidine had a stronger antibacterial activity to S. pneumoniae, S. pyogenes, MSSA, MSSE and B. catarrhalis. Conclusion: Cefathiamidine has a stronger antibacterial and bactericidal activity to Gram's positive cocci and a very strong antibacterial activity to enterococci too. |
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| Keywords: | Cefathiamidine antibacterial activity bactericidal activity MIC MBC |
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