丙泊酚瑞芬太尼静脉麻醉在腹腔镜胆囊切除术中的应用研究

目的：进一步探讨丙泊酚瑞芬太尼静脉麻醉在腹腔镜胆囊切除术中的应用效果。方法：选取本院2010年12月-2012年6月收治的48例实施腹腔镜胆囊切除术的患者为研究对象,随机分为观察组和对照组,每组24例。观察组给予丙泊酚静脉复合瑞芬太尼进行麻醉,对照组给予丙泊酚静脉复合芬太尼进行麻醉,观察两组血流动力学变化、自主呼吸恢复、拔除气管导管时间、苏醒后躁动和恶心呕吐的发生率。结果：观察组自主呼吸恢复时间、拔除气管导管时间均明显短于对照组（P〈0.05）;观察组术后躁动高于对照组（P〈0.05）;观察组血流动力学无明显变化;两组恶心呕吐发生率相当。结论：丙泊酚静脉复合瑞芬太尼全麻用于腹腔镜胆囊切除术是一种安全、高效、并发症较少的麻醉方法。

The Study of Propofol Compound Remifentanil Intravenous Anesthesia in Laparoscopic Cholecystectomy

Objective：To further explore propofol compound remifentanil intravenous anesthesia in the application of laparoscopic cholecystectomy.Method：The data of ourhospital from December 2010 to June 2012 to 48 cases of patients with laparoscopic cholecystectomy anesthesia were randomized equally into 2 groups：observation group and control group,each group of 24 cases.The observation group using propofol compound remifentanil intravenous anesthesia,the control group using propofol compound fentanil intravenous anesthesia.Each group observe hemodynamic changes,spontaneous breathing time,drawing the endotracheal tube time,incidence of restless during postanaesthetic recovery,postoperative nausea and vomiting.Result：The results showed that the time of spontaneous breathing,drawing the endotracheal tube,in observation group was significantly lower than that in control group（P〈0.05）.The incidence of adverse effect of postoperative nausea and vomiting in control group was lower significantly than that in observation group（P〈0.05）.There was no difference on the incidence of postoperative nausea and vomiting in each group.There was no obvious change in the observation hemodynamic changes.Conclusion：Propofol compound remifentanil intravenous anesthesia in laparoscopic cholecystectomy with surgical trauma in small,the time is short,less bleeding,easy to accept patients etc,and is worth clinical promotion.