库血红细胞变形性的实验研究＊

目的：观察库血在储存期间红细胞变形性的变化，为临床输血治疗提供参考依据。方法：血样来源于10例健康献血者的新鲜全血各200ml，于储存期的0d、1d、3d、5d、7d、14d、21d、28d分别检测红细胞变形性的相关指标（变形指数、刚性指数和聚集指数）。结果：血液储存5d时红细胞变形指数和刚性指数明显升高，聚集指数在7d时明显升高。三者均随时间延长呈增高趋势。结论：临床输血需谨慎，微循环障碍的患者应尽量选择5d之内的血液输注。

Experimental Research on Erythrocyte Deformability of Banked Blood

Objective：To observe change of erythrocyte deformability during storage of banked blood.Method：Blood samples（200 ml/bag）were collected respectively from ten healthy men.The relevant indicators of erythrocyte deformability（deformability index,stiffness index ,aggregation index） had been detected at 0 d,1 d,3 d,5 d,7 d,14 d,21 d,28 d.Result：Deformability index and stiffness index were significantly increased at 5 d, aggregation index was significantly increased at 7 d.they were were gradually increased with time prolong during storage of banked blood.Conclusion：It should serve as a caution to clinical transfusion.blood should be infusion to patient of microcirculatory failure when its storage time is less than 5 d.