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Immunosuppressive Therapy for External Ocular Inflammatory Disease
Authors:C. Stephen Foster
Affiliation:From the Harvard Medical School, Massachusetts Eye and Ear Infirmary, Eye Research Institute of Retina Foundation, Boston.
Abstract:Fourteen patients with progressive ocular inflammation and destructive lesions, unresponsive to conventional therapy, were treated with systemic immunosuppression. Ten patients had connective tissuelvasculitis diseases; two, cicatricial pemphigoid; and two, bilateral Mooren's corneal ulcers. Control of underlying systemic disease by immunosuppression resulted invariably in concomitant control of ocular inflammation and destruction. Encouraging results were obtained in the patients with cicatricial pemphigoid and those with bilateral Mooren's ulcers.
Keywords:cicatricial pemphigoid  connective tissue disease  immunosuppression  Mooren's ulcer  vasculitis
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