| 正交试验优选复方消痤颗粒的提取工艺 |
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| 引用本文： | 梁丹,陈卫卫,徐冬英,周吴萍. 正交试验优选复方消痤颗粒的提取工艺[J]. 中国现代应用药学, 2010, 27(11): 1002-1005 |
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| 作者姓名： | 梁丹 陈卫卫 徐冬英 周吴萍 |
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| 作者单位： | 1.广西中医学院药学院，南宁 530001；2.广西工学院生物与化学工程系，广西 柳州 545006 |
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| 基金项目： | 广西高校人才小高地建设创新团队资助计划 |
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| 摘 要： | 目的优选复方消痤颗粒的最佳提取工艺。方法以得膏率和芍药苷含量为考察指标,以加水倍数、煎煮时间和煎煮次数为主要影响因素,采用正交试验法优选提取工艺。结果复方消痤颗粒剂的最佳提取工艺为加12倍量的水,煎煮3次,每次煎煮1 h。结论本实验优选出的工艺稳定,经济,可行。
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| 关 键 词： | 复方消痤颗粒 正交试验 提取工艺 芍药苷 高效液相色谱法 |
Optimal Extraction of Xiaocuo Granules by Orthogonal Design |
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| LIANG Dan,CHEN Weiwei,XU Dongying,ZHOU Wuping. Optimal Extraction of Xiaocuo Granules by Orthogonal Design[J]. The Chinese Journal of Modern Applied Pharmacy, 2010, 27(11): 1002-1005 |
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| Authors: | LIANG Dan CHEN Weiwei XU Dongying ZHOU Wuping |
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| Affiliation: | 1.Guangxi Traditional Chinese Medical University, Nanning 530001, China; 2.Department of Biological and Chemical Engineering, Guangxi University of Technology, Liuzhou 545006, China |
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| Abstract: | OBJECTION The extraction of Xiaocuo granules was optimized. METHODS With the extraction rate and contents of paeoniflorin as the index, orthogonal test was used to evaluate the extraction. The main influential factors of extraction effect included the quantity of water, extraction times and extraction time. RESULTS The optimal condition was adding 12 times of water for 3 times and 1 hour for each time. CONCLUSION The optimized extraction is stable, economical and feasible. |
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| Keywords: | Xiaocuo granules orthogonal test extraction paeoniflorin HPLC |
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