甲亢患者治疗前后血清FT3、FT4和SIL-2R水平的变化及临床意义

目的：探讨了甲亢患者治疗前后血清FT3、FT4和SIL-2R水平的变化及临床意义。方法：分别应用放免法和酶联免疫法对55例甲亢患者进行了治疗前后血清FT3、FT4和SIL-2R水平的变化观察,并与35名正常健康人作比较。结果：治疗前血清FT3、FT4和SIL-2R水平非常显著地高于正常人组（P〈0.01）,经治疗后3个月则与正常人比较无显著性差异（P〉0.05）,血清SIL-2R水平与FT3、FT4呈明显正相关（r=0.6018、0.6117,P〈0.01）。结论：检测甲亢患者血清FT3、FT4和SIL-2R水平的变化,对观察疗效和预后判断有一定的临床使用价值。

Clinical Significance of Changes of Serum FT3, FT4 and SIL-2R Levels After Treatment in Patients with Hyperthyroidism

Objective To explore the clinical significance of changes of serum FT3,FT4,SIL-2R levels after treatment in patients with hyperthyroidism.Methods Serum FT3,FT4,TSH(with RIA) and SIL-2R(with ELISA) levels were measured in 55 patients with hyperthyroidism both before and after treatment as well as in 35 controls.Results Before treatment,in the patients the serum FT3,FT4,SIL-2R levels were significantly higher than those in the controls(P<0.01).After treatment for 3 months the serum FT3,FT4,SIL-2 levels were not significantly different from those in controls(P>0.05).Conclusion Detection of serum FT3,FT4,SIL-2R levels is valuable for treatment outcome prediction in patients with hyperthyroidism.