胃间质瘤20例临床分析

目的 提高对胃间质瘤临床特点和诊治方法的认识.方法 回顾性分析我院2006年1月～2010年3月收治的20例胃间质瘤患者的临床资料.结果 胃间质瘤患者临床表现不一,缺乏典型临床表现,首发症状主要为上消化道出血、上腹疼痛或饱胀不适、上腹鄙烧灼感等,中位发病年龄为48岁,术前主要借助超声内镜初步诊断,术后经病理和免疫组化检查确诊,CD117和CD34是最主要的免疫组化检测指标,阳性率分别达90%和85%.结论 胃间质瘤的发病年龄趋向年轻化,对于中青年出现上消化道出血及上腹痛等消化系统症状者,应考虑胃肠道间质瘤的可能,并行相关辅助检查;超声内镜是术前初步诊断胃问质瘤的首选辅助检查;手术治疗是目前胃间质瘤的主要治疗方法.

Clinical analysis for 20 patients with gastric stromal tumors

Objective Purpose To improve the recognition of clinical features and diagnosis of gastric stromal tumors. Methods The clinical datas of 20 patients with gastric stromal tumors admitted in our hospital between Jan. 2006 to Mar. 2010 were analyzed retrospectively. Results The Clinical manifestations of 20 patients with GST were various without typical symptom, and most were the upper GI bleeding, abdominal pain, bloating, or burning sensation and so on. The middle morbidity age is 48-year-old. The diagnosis before operation is mainly depended on Endoscopic ultrasound, and a delimited diagnosis can be made with the help of pathological and immnnohistochemieal examination after operation. CD117 and CD34 are the main immune markers, and the positive rates are 90% and 85% respectively. Conclusion The morbidity age of GST has a young tendency. Therefore,when we meet the young and the middle-aged who have these sysptoms related to GST,such as the upper GI bleeding, abdominal pain and so on,we should add GST into our considerations and suggest the patients to do corresponding examinations. Endoscopic ul- trasound should be chosen firstly for primary diagnosis before operation and operation is the mainly treatment for GST nowadays.