| 紫外分光光度法测定塞曲司特片的溶出度 |
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| 引用本文： | 卓文海,薛兴奎,成蓉,孔丽丽.紫外分光光度法测定塞曲司特片的溶出度[J].齐鲁药事,2008,27(1):25-26. |
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| 作者姓名： | 卓文海 薛兴奎 成蓉 孔丽丽 |
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| 作者单位： | 山东鲁抗医药集团有限公司,山东,济宁,272000 |
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| 摘 要： | 目的建立紫外分光光度法测定塞曲司特片的溶出度。方法于400~200nm波长处扫描,确定塞曲司特在266nm处有最大吸收。结果塞曲司特浓度与吸光度值A呈良好的线性关系,线性范围4~20μg.mL-1(r=0.9994),平均回收率为100.2%,RSD为0.45%(n=3)。结论该方法测定塞曲司特片溶出度,结果准确,重现性好。
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| 关 键 词： | 塞曲司特片 溶出度 紫外分光光度法 |
| 文章编号： | 1672-7738（2008）01-0025-02 |
Dissolution determination of Seratrodast Tablets by UV spectrophotography |
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| ZHUO Wen-hai,XUE Xing-kui,CHENG Rong,KONG Li-li.Dissolution determination of Seratrodast Tablets by UV spectrophotography[J].qilu pharmaceutical affairs,2008,27(1):25-26. |
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| Authors: | ZHUO Wen-hai XUE Xing-kui CHENG Rong KONG Li-li |
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| Abstract: | OBJECTIVE To establish an UV spectrophotography method for dissolution determination of Seratrodast tablets.METHODS To scan in the wavelength range of 400~200nm,and make sure Seratrodast had the largest absorption at wave length of 266nm.RESULTS The absorption was linear in the concentration range of 4~20μg·mL-1(r=0.9994).The average recovery was 99.9%,RSD=0.45%(n=3).CONCLUSION The method was good,accurate and reproducible. |
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| Keywords: | Seratrodast Tablets dissolution UV spectrophotography |
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