普外科311例围手术期抗菌药物应用调查

目的：调查普外科围手术期抗菌药物应用现状,探讨抗菌药物的合理应用.方法：对311例普外科患者围手术期抗菌药物应用进行回顾性分析.结果：308例患者使用了抗菌药物,预防用药的给药时机在术前2h内的占65.0%,术后预防用药占99.0%;喹诺酮类药物使用率最高,其次是硝基咪唑类、三代头孢菌素类;术后单用、二联、三联应用抗菌药物的比例分别为64.3%,37.4%,1.0%,手术后24.4%的患者用药时间＞7d.结论：普外科普遍采用抗菌药物预防手术感染,但严格按围手术期预防用药原则应用者少,必须加强抗菌药物围手术期应用的管理.

Survey in 311 cases of antibiotics use during perioperative period of general surgery

Objective:To discuss the situation and the rationality of antibiotics use in general surgery during perioperative period.Method:311 cases of patients used antibiotics during Perioperative period was retrospectively analyzed.Results:Antibiotics was used in 308 patients.Of all antibiotics used,202 patients received antibiotics in two hours before the operation.Quinolones were used most frequently,nitroimidazoles were the second,then were cephalosporins.64.3% of patients received single antibiotics treatment,and 37.4% and 1.0% of all patients received 2 and 3 kinds of antibiotics combined therapy respectively.24.4% of the patients were treated with antibiotics formore than 7 days.Conclusions:It is common that antibiotics are used to prophylacte surgical infection in general surgery.It is important to strengthen the management of antibiotics use during perioperative period.