| Th9细胞与自身免疫性疾病 |
| |
| 引用本文： | 杨帆,伍伟锋.Th9细胞与自身免疫性疾病[J].国际免疫学杂志,2010,33(5):350-353. |
| |
| 作者姓名： | 杨帆 伍伟锋 |
| |
| 作者单位： | 广西医科大学第四附属医院心内科,柳州,545005 |
| |
| 基金项目： | 国家自然科学基金资助项目 |
| |
| 摘 要： | Th1、Th2、Th17和调节性T细胞（Treg）亚群是CD4＋T细胞亚群中的重要成员,其参与了人类及动物自身免疫性疾病的发病过程.既往认为,IL-9是由CD4＋Th2细胞分泌的细胞因子,是机体免疫应答中重要的调节因子.最近研究表明,机体内可能存在着一群新型的具有分泌IL-9和IL-10能力的CD4＋Th细胞亚群,称之为＂Th9＂细胞.该细胞亚群与自身免疫性疾病的相关性尚不清楚.
|
| 关 键 词： | Th9细胞 自身免疫性疾病 |
Th9 cells and autoimmune diseases |
| |
| YANG Fan,WU Wei-feng.Th9 cells and autoimmune diseases[J].International Journal of Immunology,2010,33(5):350-353. |
| |
| Authors: | YANG Fan WU Wei-feng |
| |
| Institution: | .( The Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou 545005, China) |
| |
| Abstract: | T helper type 1 ( Th1 ), Th2, Th1 7 and the Treg are important members of Helper CD4 + T-cell, which participate in the pathogenesis of autoimmune diseases in humans and animal models. IL-9 was primarily recognized as a product of CD4 + Th2 cells and an important regulatory cytokine in immunologic responses. Recent data suggest that a distinct population of IL-9 and IL-10 producing helper CD4+ T-cells, named Th9, may exist. The role of Th9 cells in autoimmune diseases is currently unknown. |
| |
| Keywords: | Th9 Autoimmune diseases |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
