| 静止型珠蛋白生成障碍性贫血平均红细胞体积与脆性 |
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| 引用本文： | 孙耀君,郑立新,李汉金,王秀芸,肖敏,郭爱华,梁艳. 静止型珠蛋白生成障碍性贫血平均红细胞体积与脆性[J]. 中国生育健康杂志, 2007, 18(3): 147-148 |
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| 作者姓名： | 孙耀君 郑立新 李汉金 王秀芸 肖敏 郭爱华 梁艳 |
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| 作者单位： | 518048,广东,深圳市福田区计划生育服务中心 |
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| 摘 要： | 目的评价外周血平均红细胞体积(MCV)以及红细胞渗透脆性试验(RBC脆性试验)在诊断静止型珠蛋白生成障碍性贫血中的临床价值。方法53例经过基因分析确诊为静止型珠蛋白生成障碍性贫血患者行外周血MCV、RBC脆性试验,评价二者在筛查静止型珠蛋白生成障碍性贫血的价值。结果53例静止型珠蛋白生成障碍性贫血患者中,MCV值小于80fl占84.9%(45/53),大于80fl占15.1%(8/53);MCV筛查的漏诊率15.1%(8/53);RBC脆性全部大于70%。结论MCV试验是筛查静止型珠蛋白生成障碍性贫血的一个重要手段,而RBC脆性试验筛查不到静止型珠蛋白生成障碍性贫血,应逐步被淘汰。
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| 关 键 词： | 静止型珠蛋白生成障碍性贫血 平均红细胞容积 红细胞脆性试验 基因诊断 |
| 修稿时间： | 2007-01-11 |
Mean corpuscular volume and RBC fragile test in 53 Patients with silent oscillation mediterranean anemia |
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| SUN Yaojun, LI Hanjin, WANG Xiuyun, et al. Mean corpuscular volume and RBC fragile test in 53 Patients with silent oscillation mediterranean anemia[J]. Chinese JOurnal of Reproductive Health, 2007, 18(3): 147-148 |
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| Authors: | SUN Yaojun LI Hanjin WANG Xiuyun et al |
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| Affiliation: | Family Planning Service Center Futian, Shenzhen 518048, China |
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| Abstract: | Objective To evaluate the clinical value of mean corpuscular volume(MCV)using peripheral blood and RBC fragile test in screening patients with silent oscillation Mediterranean anemia. Methods MCV and RBC fragile test were performed among 53 patients with silent oscillation Mediterranean anemia confirmed by gene analysis.Results Of the 53 patients,there were 45 patients whose MCV val- ue was lower than 80fl and 8 patients greater than 80fl.The rate of missed diagnosis of MCV was 15%.All RBC fragile tests are higher than 70%.Conclusion MCV is an important method in screening patient with silent oscillation Mediterranean anemia,while RBC fragile test is not. |
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| Keywords: | Silent oscillation Mediterranean anemia(MCV) RBC fragile test |
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