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Unusual locations for differentiated thyroid cancer nodal metastasis
Affiliation:1. Department of General Surgery, Louisiana State University Health Sciences Center, Shreveport, LA, USA;2. Division of Head and Neck Endocrine Surgery, Department of Otolaryngology – Head and Neck Surgery, School of Medicine, The Johns Hopkins University, Baltimore, MD, USA;3. Department of Pathology, School of Medicine, The Johns Hopkins University, Baltimore, MD, USA
Abstract:Lymph node metastasis is common in differentiated thyroid cancer especially papillary thyroid cancer. Presence of lymph node metastasis does not have an impact on survival in younger patients. Therapeutic central and lateral neck dissection in the presence of clinically or radiologically evident lymph nodes has resulted in good overall survival. However, disease persistence in the lymph node/early recurrences may be seen in patients owing to lymph nodes that may be missed during the initial neck dissection. These observed locations are retropharyngeal and parapharyngeal nodal location, retro carotid location, sublingual, axillary, and intraparotid locations, supraclavicular and superficial to the sternothyroid muscle. We aim to highlight these locations with the goal to minimize persistence or early recurrence of disease at these locations.
Keywords:Differentiated thyroid cancer  Papillary thyroid cancer  Nodal metastasis  Neck dissection  Recurrent papillary thyroid cancer
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