Mechanisms of action of Sri Lankan herbal medicines used in the treatment of diabetes: A review |
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| Affiliation: | 1. Department of Biomedical Science, Faculty of Health Sciences, KIU, Koswatta, Battaramulla 10120, Sri Lanka;2. Department of Allied Health Sciences, Faculty of Medical Sciences, University of Sri Jayewardenepura, Sri Soratha Mawatha, Nugegoda 10250, Sri Lanka;1. Malaysian Palm Oil Board, Persiaran Institusi, Bandar Baru Bangi, 43000 Kajang, Selangor, Malaysia;2. Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia;3. Malaysian Palm Oil Council, Jalan Perbandaran, 47301 Kelana Jaya, Selangor, Malaysia;1. Department of Persian Medicine, School of Persian Medicine, Babol University of Medical Sciences, Babol 4717647745, Iran;2. Traditional Medicine and History of Medical Sciences Research Center, Health Research Institute, Babol University of Medical Sciences, Babol 4717647745, Iran;3. School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran 1985717443, Iran;4. Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan 4934174515, Iran;1. Integral Health Care, Regional University of the Northwest of the State of Rio Grande do Sul (UNIJUÍ) and University of Cruz Alta (UNICRUZ), Ijuí 98700-000, RS, Brazil;2. Experimental Neuroscience Laboratory (LaNEx), University of Southern Santa Catarina, Palhoça 88137-270, SC, Brazil;3. Laboratory of Neurobiology of Inflammatory and Metabolic Processes, University of Southern Santa Catarina, Tubarão 88704-900, SC, Brazil;4. Integrative Physical Therapy Residency, Philadelphia University Center, Londrina 86020-000, PR, Brazil;5. Laboratory of Exercise Physiopathology, Department of Life Sciences (DCVida), Regional University of the Northwest of the State of Rio Grande do Sul (UNIJUÍ), Ijuí 98700-000, RS, Brazil;1. Department of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan 25200, Pahang, Malaysia;2. Department of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan 25200, Pahang, Malaysia |
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| Abstract: | Natural plant-based remedies for diabetes mellitus have been proven to be safe and effective alternatives to Western medications, and details about more than 400 plants are available in the literature. Sri Lanka is a tropical country which is blessed with many natural plant products that can be utilized for the treatment of diabetes. But the knowledge of these plant-derived remedies, especially their doses, mechanism of action and toxicity has not been extensively researched. Therefore, this review focuses on documenting the plant-based remedies that the Sri Lankan Aurvedic physicians use and the extent of research that has been carried out on each of these plant-based remedies. |
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| Keywords: | Antidiabetic Diabetes mellitus Antioxidant Mechanism Natural plants Review |
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