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Pathology and Pathogenesis of T-Cell Lymphoma
Institution:1. Department of Hematopathology, MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, Texas, 77030, US;1. The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA;1. University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 429, Houston, TX 77030, USA;1. Department of Hematology, Niguarda Cancer Center, Niguarda Hospital, Milan, Italy;1. Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY, 14263, USA;1. The University of Texas MD Anderson Cancer Center, Houston, Texas, USA;1. Division of Oncology, Washington University School of Medicine, St Louis, MO, USA
Abstract:Peripheral T cell lymphomas (PTCLs) are a heterogeneous and often clinically aggressive group of neoplasms derived from mature post-thymic T lymphocytes. These neoplasms are rare and usually diagnostically challenging. Our understanding of the pathogenesis of PTCL is increasing and this improved knowledge is leading us to better molecular characterization, more objective diagnostic criteria, more effective risk assessment, and potentially to better treatments for these neoplasms.
Keywords:Angioimmunoblastic T cell lymphoma  follicular T helper  anaplastic large cell lymphoma  indolent T cell lymphomas  intestinal T cell lymphoma
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