State-of-the-art-myocardial perfusion stress testing: Static CT perfusion |
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| Institution: | 1. Centro Cardiologico Monzino, IRCCS, Milan, Italy;2. Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milan, Milan, Italy;1. Centro Cardiologico Monzino, IRCCS, Milan, Italy;2. Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA;3. Institute of Cardiovascular Disease, Department of Emergency and Organ Transplantation, University Hospital Policlinico, Bari, Italy;4. Department of Radiology, Utrecht University Medical Center, Utrecht, the Netherlands;5. The Johns Hopkins Hospital, Baltimore, USA;6. MTA-SE Cardiovascular Imaging Research Group (CIRG) Heart and Vascular Center, Semmelweis University, Budapest, Hungary;7. Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, USA |
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| Abstract: | Large multicenter studies and meta-analysis have documented the diagnostic accuracy and the prognostic implications of stress echocardiography, cardiac magnetic resonance and, mainly, nuclear stress tests. However, none of them provides a comprehensive anatomical and functional evaluation within the same study as stress CT perfusion. Myocardial CT perfusion is the only non-invasive modality that allows to quantifying coronary stenosis and determining its functional relevance, constituting a potential “one-stop-shop” method for the diagnosis and global management of patients with known or suspected coronary artery disease. In comparison with the dynamic modality, that requires increased radiation, precise acquisition protocols and dedicated post-processing softwares, static CT perfusion was associated with less radiation exposure, non-inferior diagnostic accuracy, easier interpretation of images and is nowadays more widely available. |
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| Keywords: | Myocardial perfusion Functional assessment CT perfusion Static modality |
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