Ethanol-metrecal diets: I. Effects of different levels of ethanol-derived kilocalories on consumption of diet,body weight and grams of ethanol ingested |
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Authors: | Tom N Tombaugh Jo W Tombaugh |
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Institution: | Psychology Department, Unit for Behavioral Medicine and Pharmacology Carleton University, Ottawa, Ontario, Canada K1S 5B6 |
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Abstract: | Three experiments investigated the relationship between ethanol consumption and the percentage ethanol-derived kilocalories contained in liquid diets. Rats were chronically maintained on diets where different concentrations of ethanol (10%, 12%, 14%) were added to Metrecal so that 41%, 49% and 57% of all kilocalories consumed were derived from ethanol. The ethanol-Metrecal diet served as the sole source of calories. Results demonstrated that rats can be maintained fromextended time periods on diets where ethanol contributed approximately 50% of the daily kilocalories. Inspection of consummatory profiles revealed that an initial decrease occurred in volume of diet consumed when levels of ethanol were increased. This was followed by a gradual increase in the level of consumption until a new asymptotic level was established. Grams of ethanol/kg of body weight remained relatively constant over the range of ethanol concentrations employed. The results were discussed in respect to three factors controlling consummatory behavior-sensory stimuli, caloric intake and quantity of ethanol ingested. |
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Keywords: | Ethanol Liquid diet Chronic ingestion Dependence Rats |
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