脑梗死急性期下肢运动功能恢复与体感诱发电位变化的关系

目的探讨体感诱发电位 (SEP)评定和预测脑梗死急性期患者下肢运动功能恢复的价值。方法按照脑血管疾病分类标准 ,选择脑梗死急性期患者 19例 (男性 13例、女性 6例 )作为病例组。同时 ,选择 18例非神经系统损伤患者 (男性 11例、女性7例 )作为对照组 ;在发病 7d内 ,检测并比较两组患者SEP的潜伏期和波幅值的改变 ;对病例组患者 ,于住院 3 0d时再次进行下肢SEP检测 ,并在两次SEP检测的同时进行下肢Fugl Meyer评定 (FMA) ,以对SEP潜伏期与FMA评分进行相关分析。 结果两组患者的下肢SEP潜伏期和波幅值差异有显著性意义 ;病例组患者住院 3 0d时的SEP潜伏期值较入院时明显缩短 (P <0 .0 1) ,并与下肢FMA评分有相关性 (r =0 .741— 0 .792 ,P <0 .0 1) ,但住院 3 0d时的SEP波幅值改变与入院时比较无显著性差异。结论脑梗死急性期患者入院时和住院 3 0d时下肢SEP潜伏期值的改变有统计学意义 ,并与FMA评分有相关性 ,说明SEP潜伏期值对预测脑梗死急性期患者下肢运动功能恢复有一定参考价值 ,但SEP波幅的敏感性较差。

Relationship of the lower limb functional recovery and somatosensory evoked potentials in the hemiplegic patients with acute cerebral infarction

ObjectiveTo explore the role of ssomatosensory evoked potential (SEP) in evaluating and predicting the lower limb motor function of patients with acute cerebral infarction.Methods19 patients (13 male, 6 female) with acute cerebral infarction diagnosed according to the standard of Chinese Classifications of the Cerebral Vascular Disease were chosen as the case group and 18 patients (11 male, 7 female) with non-nerve system injury were taken as the control group. All patients of two groups were received SEP test within 7 days after onset and latency and amplitude values of SEP of two groups were compared. To the case group, SEP was tested again at 30th day after admission, the Fugl-Meyer assessment (FMA) was also carried out at same times of two SEP tests, and the correlation of SEP and FMA scores was analyzed.ResultsThe difference of latency and amplitude value of SEP test between the case group and control group was significantly ( P<0.01). The latency value of SEP in lower limb was correlated with FMA scores ( P<0.01). But the amplitude value was no difference between the onset and 30th day after admission in the case group.ConclusionSEP is sensitive in the acute stage of stroke. SEP has significant value for predicting the prognosis of patients with acute cerebral infarction and correlates with the clinical FMA scores. The value of amplitude is not sensitive.