| 术中应用电生理检测研究普鲁卡因封闭对神经的保护作用 |
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| 引用本文： | 尹宗生,顾玉东.术中应用电生理检测研究普鲁卡因封闭对神经的保护作用[J].中华手外科杂志,1996,12(1):8-10. |
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| 作者姓名： | 尹宗生 顾玉东 |
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| 作者单位： | 安徽医科大学第一附属医院骨科(尹宗生!230022合肥，董吟林!230022合肥，高学纯!230022合肥)，上海医科大学手外科研究所(顾玉东，沈丽英) |
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| 摘 要： | 目的：旨在验证临床应用普鲁卡因封闭对神经的保护作用。方法：对３２根周围神经，其中神经移位术选用的动力神经１８根，损伤后行神经吻合的１４根。在术中用普鲁卡因封闭神经，并在封闭前后进行电生理监测。结果：普鲁卡因封闭后被检神经的体感诱发电位（ＳＥＰ）的潜伏期（Ｌａｔ），比封闭前延长１５．３％，波幅（Ａｍｐ）降低１８．５％。神经封闭后ＳＥＰ的潜伏期延长和波幅降低，与封闭前比较，差异有显著性意义（Ｐ〉０．０
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| 关 键 词： | 电生理 周围神经 普鲁卡因 |
The protective effect of procaine blocking on nerve:an electrophysiological study during operation |
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| Yin Zongsheng,Gu Yudong,Shen Liyin,at al.The protective effect of procaine blocking on nerve:an electrophysiological study during operation[J].Chinses Journal of Hand Surgery,1996,12(1):8-10. |
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| Authors: | Yin Zongsheng Gu Yudong Shen Liyin at al |
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| Institution: | Yin Zongsheng,Gu Yudong,Shen Liyin,at al . Department of orthopedics,The First Affiliated Hospital,Auhui Medical University,Hefei 230022. |
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| Abstract: | In orde. to evaluate the protective effect of procaine blatlcing to nerve clianically . Electrophysi- ological examinations before and after procaine blocking were done in 32 nerves during operation, eighteen of which were donor nerves used to be transferred and fourteen were impaired ones .After procaine blocking the latency of SEP ( somatosensory evoked potentials )lengthened by 15 . 3 % and the amplitude lowered by 18 . 5 % . Compared with that before bloclcing, the difference were signficant ( P < 0 . 01 , p < 0 . 05 ) . The waves of SEP disappeared after procaine blocking in some cases ( 28 . 1 % , 9/ 32 ) . It is concluded that procaine blocking prevented conduction of harmful impulses and protected the nerve neurons . |
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| Keywords: | Electrophysiology Peripheral nerve Procaine |
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