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天然产物多级膜与高压差提取器联用的设计与开发
引用本文:宋力飞,李曼莎,刘乡乡.天然产物多级膜与高压差提取器联用的设计与开发[J].世界科学技术,2009,11(6):897-900.
作者姓名:宋力飞  李曼莎  刘乡乡
作者单位:广州泽力医药科技有限公司,广州,510663 
基金项目:国家科技部等14个部委和广东省人民政府共同主办的"2009'传统医药国际科技大会暨博览会"同期活动五--"现代中药制药装备研究开发论坛"推荐论文:国家科技型中小企业技术创新基金无偿资助项目(07C26214401795):连续式高效低温提取浓缩器的应用开发研究国家科技部支撑计划子课题(2006BAI06A04-01):中药现代提取分离关键技术及装,广东省技术创新项目(200872203):全自动中药低温提取分离浓缩器的开发应用,广东省科技厅粤港关键领域重点突破项目(2009498C1402):模块化集装箱式提取分离浓缩器的研究 
摘    要:天然产物高压差提取分离浓缩器的核心技术在于多级膜与高压差提取器的联用设计。它是通过合理的结构设计、流程与自控设计以及排污和安装设计,将高压差提取、微滤澄清、超滤分离、纳滤或反渗透浓缩、在线清洗、过程自控等多技术单元进行组合,形成完整的技术及成套装备,可较好地实现中药提取物全过程低温(20℃以下)制备,达到洁净区流程化生产的目的。

关 键 词:高压差提取  多级膜  联用设计  分离浓缩  成套装备

Design and Development of the Combined Multi-membrane and High-pressure Differential Extract Combined Technique for Natural Products
Song Lifei,Li Mansha,Liu Xiangxiang.Design and Development of the Combined Multi-membrane and High-pressure Differential Extract Combined Technique for Natural Products[J].World Science and Technology(Modernization of Traditional Chinese Medicine),2009,11(6):897-900.
Authors:Song Lifei  Li Mansha  Liu Xiangxiang
Institution:(Guangzhou Ze Li Pharmted Co.Ltd., Guangzhou 510663, China)
Abstract:The core technique of the high-pressure differential extraction, separation and concentration equipment for natural products is the design of multi-level membrane and high-pressure differential extraction in combination. Based on the rational structrul design, process and automation design, as well as sewerage and installation design, this technique makes up various technical steps, including high-pressure differential extraction, microfihration clarification, ultrafihration, nonofihration or reverse osmosis concentraion, on-line cleaning process, and procedure auto control technique, thus forming a complete set of techniques and equipments. This makes it possible to prepare the traditional Chinese medicine extract at low temperature (20 ℃ or less) during the entire process, thus fulfilling the scheduled production in a clean area.
Keywords:High-pressure differential extract technique  Multi-level membrane  Combined design  Separation and concentration  Sets of equipment
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