头颈部癌症病人术后生活质量研究

目的 :评价头颈部癌症病人术后 1a内的生活质量 (QOL)及其影响因素。方法 :应用欧洲研究和治疗癌症组织核心生活质量调查表 3 0 -项 (EORTCQLQ -C3 0 )和医院焦虑和抑郁等级(HADS) ,评估分析手术或手术加放射治疗的头颈部癌症病人88例术后 1a的QOL。结果 :头颈部癌症病人治疗结束后 1个月与诊断时比较 ,功能维度中的生理活动机能和全身QOL、症状维度中的疲劳、单项中的食欲丧失和便秘所引起的QOL变化有统计学意义 (P <0 .0 1或P <0 .0 5 ) ;治疗结束后 6月与诊断时比较 ,功能维度中的情感活动机能、单项中的失眠所引起的QOL变化有差异 (P <0 .0 1) ;治疗结束后 6个月与 1个月比较 ,症状维度中的疼痛所引起的QOL有差异 (P <0 .0 1) ;治疗结束后 12个月与 6个月比较 ,症状维度中的恶心和呕吐所引起的QOL变化有差异 (P <0 .0 5 )。结论 :治疗后 1个月～ 6个月 ,头颈部癌症病人的生活质量较低 ,护理应提供临床治疗干预和心理干预。

A Study on Life Quality of Post-surgical Patients With Cephalocevical Cancer

Objective: to assess the quality of life (QOL) of cephalocevical cancer patients after accepted operation within one year and its relevant factors. Methods: QOL of a total of 88 cephalocevical cancer patients who had accepted either surgery or surgery combined with radiotherapy within one year were evaluated by adopting both European Organization for Research and Treatment of Cancer core Quality of Life Questionnaire (EORTC QLQ-C30) and Hospital Anxiety and Depression Scale (HADS). Results: compared the condition when the time of their diagnosis were just made with the condition of one month later after they had accepted either surgery or surgery combined with radiotherapy, there were statistical significance between them in terms of their physiological activity function and QOL of the body, and changes of QOL leaded by fatigue, loss of appetite, and constipation (P<0.01 or P<0.05). At the sixth month after patients finished the treatment compared with patients of one month after the treatment, there was significant difference in terms of their social activity and QOL induced by pain (P<0.01). Compared patients of 12 months after treatment with 6 months after treatment, there was significant difference in terms of their QOL induced by nausea and vomiting (P<0.05). Conclusion: cephalocevical cancer patients had poor quality of life in the first month to sixth month after their treatment. Nursing staffs should provide both clinical therapeutic and psychological intervention for them.