非酒精性脂肪性肝病患者人体脂肪成分指标的变化

目的 调查非酒精性脂肪性肝病（NAFLD）患者人体成分及其变化情况,为NAFLD的早期预防和治疗提供科学依据。 方法 使用百利达MC180人体成分分析仪对148例NAFLD患者进行人体成分分析,获得体质量、身高、体质指数（BMI）、肌肉量、脂肪量、骨量、脂肪率及其分布、内脏脂肪等级等指标。 结果 本组NAFLD患者高体脂肪含量发生率为51.4%,其中,18~39岁患者高体脂肪含量发生率（86.3%）显著高于中老年患者（分别为39.3%和24.4%）;男性患者肌肉量、骨量、内脏脂肪等级均高于女性,女性脂肪量和体脂肪率高于男性（P<0.01）;男女性患者随年龄增加体脂肪率和躯体脂肪率降低（P<0.01）,男性患者上肢脂肪率和女性患者上、下肢脂肪率均随年龄增加而降低（P<0.01）;本组NAFLD患者骨量低于标准发生率,为49.3%,NASH发生率为20.3%。 结论 NAFLD患者人体成分的变化主要表现在体脂肪率增加和骨量降低,并且年轻患者高体脂肪含量发生率更高。

Body compositions in patients with nonalcoholic fatty liver disease

Objective To analyze the characteristics of human body compositions in patients with non-alcoholic fatty liver disease（NAFLD）,in order to provide scientific basis for the early prevention and therapeutic schedule. Methods The TANITA MC 180 body composition analyzer was applied to measure body compositions,including weight,height,body fat ratio,fat mass,muscle mass,bone mass,visceral fat rating,BMI and some other indexes in 148 patients with NAFLD. Results The high body fat rate in 148 patients with NAFLD was 51.4%,and among them,the high body fat rate in young（18 to 39 year old） patients was 86.3%,significantly higher than 39.3% and 24.4% in middle and old age patients;the muscle mass,bone mass and visceral fat rating in male patients were higher than those in female,and the fat mass and body fat ratio in female were higher than in male （P<0.01）;The body fat ratio and trunk body ratio decreased as the patients with NAFLD got elderly（P<0.01）,and the upper limbs fat ratio and four limbs fat ratio in female patients decreased as the patients got elderly（P<0.01）;the incidence of bone mass below the standard was 49.3%,and the incidence of NASH was 20.3% in this series. Conclusion The main changes of the body compositions among patients with NAFLD are the increase of the body fat ratio and the decrease of the bone mass,and we should take it into consideration that the incidence of excess body fat is higher among the young patients with NALFD.