Adrenomedullin assay and its clinical significance |
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Authors: | Parlapiano C Paoletti V Campana E Labbadia G Giovanniello T Califano F Pantone P Clemente G Donnarumma L Musca A |
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Affiliation: | Istituto II Clinica Medica, Policlinico Umberto I, Università degli Studi La Sapienza di Roma, Italy. |
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Abstract: | Adrenomedullin (Am) is a recently discovered peptide, first purified from pheochromocytoma specimens, with a chemical structure similar to that of CGRP and amylin. Adrenomedullin is present in numerous human body tissues and its powerful vasodilatatory activity is thought to play an essential role in cardiovascular and renal homeostasis. |
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