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A phase 1b dose expansion study of the pan-class I PI3K inhibitor buparlisib (BKM120) plus carboplatin and paclitaxel in PTEN deficient tumors and with dose intensified carboplatin and paclitaxel
Authors:Lillian M. Smyth  Kelsey R. Monson  Komal Jhaveri  Alexander Drilon  Bob T. Li  Wassim Abida  Gopa Iyer  John F. Gerecitano  Mrinal Gounder  James J. Harding  Martin H. Voss  Vicky Makker  Alan L. Ho  Pedram Razavi  Alexia Iasonos  Philip Bialer  Mario E. Lacouture  Jerrold B. Teitcher  Joseph P. Erinjeri  Nora Katabi  Matthew G. Fury  David M. Hyman
Affiliation:1.Department of Medicine, Weill Cornell Medical College, Memorial Sloan Kettering Cancer Center (MSKCC),New York,USA;2.Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center (MSKCC),New York,USA;3.Department of Psychiatry, Memorial Sloan Kettering Cancer Center (MSKCC),New York,USA;4.Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center (MSKCC),New York,USA;5.Department of Radiology, Memorial Sloan Kettering Cancer Center (MSKCC),New York,USA;6.Department of Pathology, Memorial Sloan Kettering Cancer Center (MSKCC),New York,USA;7.Oncology Clinical Sciences, Regeneron Pharmaceuticals,Tarrytown,USA
Abstract:
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