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幽门螺杆菌感染对心血管病患者脂代谢的影响
引用本文:陈良海,李刚,李代渝,刘远厚,罗兴林,薛莉. 幽门螺杆菌感染对心血管病患者脂代谢的影响[J]. 中国煤炭工业医学杂志, 2001, 4(2): 93-94
作者姓名:陈良海  李刚  李代渝  刘远厚  罗兴林  薛莉
作者单位:四川省泸州市,泸州医学院附属医院心内科 646000
摘    要:目的探讨HP感染对脂代谢的影响。方法用酶联免疫法(ELISA)测定心血管疾病患者192例的血清HPIgG、TC、TG、ApoA1、ApoB、Lp(a)、HIDL-C、LDL-C。结果HP感染者108例,未感染HP者84例,t检验显示HP感染可明显升高血清TG和ApoB浓度(P<0.05)。结论HP感染可引起脂代谢紊乱,可能机制为HP感染抑制了脂蛋白酶的活性与分泌。

关 键 词:幽门螺杆菌感染 血脂代谢 心血管病 影响 ELISA
文章编号:1007-9564(2001)02-0093-02
修稿时间:2000-10-19

EFFECT OF HELICOBACTER PYLORI INFECTION ON THE LIPID METABALISM IN PATIENTS WITH CARDIO.VASCULAR DISEASES
Chen Lianghai,Li Gang,Li Daiyu,et al.. EFFECT OF HELICOBACTER PYLORI INFECTION ON THE LIPID METABALISM IN PATIENTS WITH CARDIO.VASCULAR DISEASES[J]. Chinese Journal of Coal Industry Medicine, 2001, 4(2): 93-94
Authors:Chen Lianghai  Li Gang  Li Daiyu  et al.
Affiliation:Chen Lianghai,Li Gang,Li Daiyu,et al. the Affiliated Hospital of Luzhou Medical College,Sichuan Province 646000
Abstract:Objective To study the effect of helicobacter pylori (HP) infection on the lipid metabolism in patients with cardiovascular diseases. Methods ELISA was employed to measure serum specific IgG antibodies to HP (HPIgG) and the serum levels of total cholesterol (TC), triglyceride (TG), apolipoprotein A1 (ApoA1), apolipoprotein B (ApoB), apolipoprotein (a) [Lp (a)], high density apolipoprotein cholesterol (HDL-c), and low density apolipoprotein cholesterol (LDL-c) in 192 patients.Results 108 patients were infected by HP, while 84 were not. T test indicated that the levels of serum TG and ApoB in the cases of HP infection were obviously increased (P<0.05). Conclusion HP infection might cause disorder in the lipid metabolism. The possible mechanism might be that the HP infection can suppress activity and secretion of lipoprotein lipase.
Keywords:Helicobacter pylori Infection Lipid Metabolism
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