The Role of Glutathione in Intestinal Dysfunction |
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| Authors: | Heather Jefferies Joan Bot Jane Coster Alizan Khalil John C. Hall Rosalie D. McCauley |
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| Affiliation: | Department of Surgery, University of Western Australia, Perth, Western Australia, Australia |
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| Abstract: | Glutathione plays an important cytoprotective role in the gut. Animal studies have demonstrated that the provision of glutathione precursors are protective for different types of free-radical-mediated cellular injury. There is a need to clarify the potential role of glutathione supplementation in ischemia–reperfusion injury and inflammatory bowel disease. More speculative is whether dietary treatment with glutathione precursors can modify the progress of colorectal cancer. |
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| Keywords: | colorectal cancer glutathione inflammatory bowel disease ischemia-repurfusion injury |
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