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Air Pollution and Postneonatal Mortality in a Tropical City: Kaohsiung,Taiwan
Authors:Shang-Shyue Tsai  Chih-Cheng Chen  Hui-Ju Hsieh  Chih-Ching Chang  Chun-Yuh Yang
Affiliation:1. Department of Healthcare Administration, I-Shou University, Kaohsiung CountyTaiwan;2. Section of Neonatology, Department of Pediatrics, Kaohsiung Chang-Gung Medical Center, Kaohsiung CountyTaiwan;3. Institute of Public Health, Kaohsiung Medical University, KaohsiungTaiwan
Abstract:With growing evidence of the association between daily mortality and air pollution in adults, it is important to investigate whether infants are also susceptible to the adverse health effects of ambient air pollutants. The purpose of this study is to examine the relationship between air pollution and postneonatal mortality in Kaohsiung, Taiwan, a large industrial city with a tropical climate, during the period 1994–2000, using a case-crossover analysis. Case–crossover analysis provides an alternative to Poisson time-series regression for studying the short-term adverse health effects of air pollution. The air pollutants examined included particulate matter (PM10), sulfur dioxide (SO2), ozone (O3), nitrogen dioxide (NO2), and carbon monoxide (CO). The risk of postneonatal deaths was estimated to increase by 4.0% per 67 μg/m3 (the interquartile range in daily ambient concentration of PM10) for PM10, 1.8% per 17.84 ppb for NO2, 5.1% per 0.31 ppm for CO, and 4.6% per 19.20 ppb for O3. Although positive, none of these associations achieved statistical significance. The established link between air pollution levels and infant mortality may not be as strong in cities with tropical climates, although other factors such as differences in pollutant mix or the underlying health of the postneonates may explain the lack of a strong association in this study. Further studies of this type in cities with varying climates and cultures are needed.
Keywords:Acute lung injury  angiopoietin-1  cytokine  NF-κB  p38 MAPK  phosgene
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