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Protective effect of the daming capsule on impaired baroreflexes in STZ-induced diabetic rats with hyperlipoidemia |
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| Authors: | Jing Ai Li-Hong Wang Rong Zhang Guo-Fen Qiao Ning Wang Li-Hua Sun Guan-Yi Lu Chao Sun Bao-Feng Yang |
| Affiliation: | 1.Department of Pharmacology, and the State-Province Key Laboratory of Biomedicine and Pharmaceutics,Harbin Medical University,Harbin,China;2.Endocrinology and Metabolism Department of the Second Affiliated Hospital,Harbin Medical University,Harbin,China |
| Abstract: | BackgroundThe Daming capsule (DMC) is a traditional Chinese medicine used to treat hyperlipoidemia. Both clinic trials and studies on animal models have demonstrated that DMC is beneficial against diabetic symptoms. Impairment of the baroreflex can cause life-threatening arrhythmias and sudden cardiac death in patients with diabetes mellitus (DM). This study was designed to elucidate the effects of DMC on baroreflexes in streptozocin (STZ)-induced diabetic rats with hyperlipoidemia. |
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