| 奥美拉唑与法莫替丁治疗消化性溃疡68例临床观察 |
| |
| 引用本文： | 熊镇南,王安. 奥美拉唑与法莫替丁治疗消化性溃疡68例临床观察[J]. 国际医药卫生导报, 2005, 11(10): 88-89 |
| |
| 作者姓名： | 熊镇南 王安 |
| |
| 作者单位： | 珠海市人民医院药剂科,广东,珠海,519000;珠海市人民医院消化诊治中心,广东,珠海,519000 |
| |
| 摘 要： | 目的观察奥美拉唑和法莫替丁治疗消化性溃疡的疗效和不良反应。方法将68例已确诊的消化性溃疡患者随机分为两组,治疗组35例用奥美拉唑20mg,每日早晨吞服,对照组33例口服法莫替丁20mg,1日2次,两组疗程为4周。结果治疗组和对照组抗溃疡有效率分别为96.0%和88.0%,两组有显著性差异(P<0.05),奥美拉唑不良反应发生率17.0%高于法莫替丁12.0%(P<0.05)。结论奥美拉唑抗溃疡有效率及不良反应发生率均高于法莫替丁,但其副作用发生轻微,不必停药,也不影响疗效,仍为目前经济、安全有效的抗消化性溃疡药物。
|
| 关 键 词： | 奥美拉唑 法莫替丁 消化性溃疡 |
| 文章编号： | 1007-1245(2005)10-0088-02 |
| 修稿时间： | 2005-02-17 |
Clinical Observe of Omeprazole and Famotidine in Treating 68 Peptic ulcer |
| |
| Xiong Zhennan,WANG An. Clinical Observe of Omeprazole and Famotidine in Treating 68 Peptic ulcer[J]. International Medicine & Health Guidance News, 2005, 11(10): 88-89 |
| |
| Authors: | Xiong Zhennan WANG An |
| |
| Affiliation: | XIONG Zhennan1 WANG An2 1Dept.of pharmacy,2 Diagnosis and Treatment center of Digestion,The people's Hospital of zhuhai,zhuhai 519000 China |
| |
| Abstract: | Objective To observe the clinical effects and adverse reactions of omeprazole and famotidine on peptic ulcer. Methods 68 patients with pepti c ulcer were randomly divided into 2 gyoups.Treated with omeprazole or famotidine respectively. The treated group received omeprazole 20mg,P.O,qd.The con- trast group received famotidine 20mg,P.O,Bid.Period of treatment for two groups were 4-week. Results 4-week effective rate of omeprazole group 96.0% and famotidine group 88.0% respectively. Indicating significant differences between the 2 groups (P<0.05). A few of adverse reactions appeared in the omeprazole group 17.0% and less in the famotidine group12.0% (P<0.05).but the adverse reactions disappeared spontaneously. Conclusion Omeprazole is still safer and more effective drug in treating pepti culcer. |
| |
| Keywords: | Omeprazole Famotidine Peptic ulcer |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
