| 4味中药对酪氨酸酶抑制作用的探讨 |
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| 引用本文： | 闫军,李昌生,陈声利,张君仁,赵天恩.4味中药对酪氨酸酶抑制作用的探讨[J].中国药房,2003(7). |
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| 作者姓名： | 闫军 李昌生 陈声利 张君仁 赵天恩 |
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| 作者单位： | 济南市皮肤病防治院 济南市250001
(闫军，李昌生，陈声利)，山东大学药学院 济南市250012
(张君仁)，山东省皮肤病性病研究所 济南市250022(赵天恩) |
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| 摘 要： | 目的 :研究14味中药对酪氨酸酶的抑制作用。方法:用50%乙醇提取中药有效成分 ,利用紫外分光光度法测定酶促反应的速度 ,以衡量其对酪氨酸酶的抑制作用。结果 :测得14条酶促反应时间曲线。结论 :13味中药对酪氨酸酶活性呈较好的抑制作用(P<0.01) ,除芦荟以外 ,其余中药不影响酶促反应的平衡。桃仁、僵蚕、芦荟抑制作用最好
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| 关 键 词： | 中药 酪氨酸酶 紫外分光光度法 抑制 |
Study on the Inhibiting Effects of 14 Kinds of Chinese Materia Medica on Tyrosinase |
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| YAN Jun,LI Changsheng,CHEN Shengli.Study on the Inhibiting Effects of 14 Kinds of Chinese Materia Medica on Tyrosinase[J].China Pharmacy,2003(7). |
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| Authors: | YAN Jun LI Changsheng CHEN Shengli |
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| Abstract: | OBJECTIVE:To inverstigate the inhibitory effects of 14 kinds of traditional Chinese medicines on tyrosinase activity METHODS:The effective components of traditional Chinese medicines were extracted by 50% ethanol The speed of enzymic catalysis of tyrosinase was determined by ultraviolet spectrophotometry to evaluate the inhibitory effects of extracts of traditional Chinese medicines RESULTS:14 reactive time curves of enzymic catalysis of tyrosinase were obtained CONCLUS_ION:13 kinds of traditional Chinese medicines in vitro showed a better inhibitive effect on tyrosinase activity(P<0 01), without influence on the equilibrium of enzymic catalysis except Aloe barbadensis Miller Prunus persica Batsch,Bombyx mori Linnaeus and Aloe barbadensis Miller showed the best inhibitory effect on tyrosinase activity |
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| Keywords: | traditional Chinese medicines tyrosinase ultraviolet spectrophotometry inhibition |
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