Primary upper small-intestinal lymphoma |
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Authors: | Dr. Khosrow Nasr MD Parviz Haghighi MD Kiumars Bakhshandeh MD Pari Abadi MD A. Lahimgarzadeh MD |
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Affiliation: | (1) Pahlavi University, Shiraz, Iran;(2) Nemazee Hospital, Shiraz, Iran |
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Abstract: | Primary upper small-intestinal lymphoma (PUSIL) has now been recognized as a distinct clinical entity with a distinct geographic distribution. Herewith are presented 40 cases of PUSIL seen at Pahlavi University Hospitals in Southern Iran. The investigation reveals the lymphoma to be predominantly a disease of those under 30 and males; the major complaints and physical findings point to an intraabdominal disease. An exception has been clubbing and osteoarthropathy. Special features of PUSIL include: (1) protein loss into the gastro-intestinal tract leading to hypoalbuminemia and edema; (2) an antibiotic-responsive diarrhea and steatorrhea; and (3) an associated abnormal heavy-chain protein. The study further stresses the importance of peroral small-intestinal biopsy and the pathologic features of this condition. |
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