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Microvascular and proteomic signatures overlap in COVID-19 and bacterial sepsis: the MICROCODE study |
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| Authors: | Rovas Alexandros Buscher Konrad Osiaevi Irina Drost Carolin Christina Sackarnd Jan Tepasse Phil-Robin Fobker Manfred Kühn Joachim Braune Stephan Göbel Ulrich Thölking Gerold Gröschel Andreas Rossaint Jan Vink Hans Lukasz Alexander Pavenstädt Hermann Kümpers Philipp |
| Affiliation: | 1.Department of Medicine D, Division of General Internal and Emergency Medicine, Nephrology, and Rheumatology, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Münster, Germany ;2.Department of Medicine A, Hematology, Oncology and Pulmonary Medicine, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Münster, Germany ;3.Department of Cardiology and Angiology, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Münster, Germany ;4.Department of Medicine B for Gastroenterology, Hepatology, Endocrinology, Clinical Infectiology, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Münster, Germany ;5.Center for Laboratory Medicine, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Münster, Germany ;6.Institute of Virology, University Hospital Münster, Von-Stauffenberg-Stra?e 36, 48151, Münster, Germany ;7.Departmenf of Intensive Care and Emergency Medicine, St. Franziskus-Hospital GmbH, Hohenzollernring 70, 48145, Münster, Germany ;8.Department of Anaesthesiology and Critical Care, St. Franziskus-Hospital GmbH, Hohenzollernring 70, 48145, Münster, Germany ;9.Department of Internal Medicine and Nephrology, University Hospital Münster Marienhospital Steinfurt, Mauritiusstr. 5, 48565, Steinfurt, Germany ;10.Department of Pulmonology, Clemens Hospital, Düesbergweg 124, 48153, Münster, Germany ;11.Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Münster, Germany ;12.Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, 6229 ER, Maastricht, the Netherlands ; |
| Abstract: | Angiogenesis - Although coronavirus disease 2019 (COVID-19) and bacterial sepsis are distinct conditions, both are known to trigger endothelial dysfunction with corresponding microcirculatory... |
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