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Ticagrelor and Dapagliflozin Have Additive Effects in Ameliorating Diabetic Nephropathy in Mice with Type-2 Diabetes Mellitus |
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| Authors: | Birnbaum Yochai Chen Huan Tran Dat Nylander Sven Ye Yumei |
| Affiliation: | 1.The Section of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA ;2.The Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, 301 University Blvd, BSB 648, Galveston, TX, 77555, USA ;3.Department of Acupuncture, First Affiliated Hospital of Nanjing Medical University, Nanjing, China ;4.School of Medicine, University of Texas Medical Branch, Galveston, TX, USA ;5.Biopharmaceutical R&D, AstraZeneca, Gothenburg, Sweden ; |
| Abstract: | Cardiovascular Drugs and Therapy - Ticagrelor and dapagliflozin can suppress the activation of the NOD-like receptor 3 (NLRP3)-inflammasome and activate AMP-activated protein kinase (AMPK). The... |
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