尿常规联合血清降钙素原检查在尿路感染鉴别诊断中的应用价值

目的探讨尿常规联合血清降钙素原(PCT)检查对于尿路感染鉴别诊断的参考价值。方法选取150例疑似尿路感染患者(观察组)和同期接受检查的110例健康体检者(对照组),均先后接受尿常规检查和PCT检查,同时进行尿细菌学检查。对比两组受检者的尿常规及PCT检查结果,以尿细菌学检查作为金标准,分析观察组患者的尿常规和PCT检查结果,对比不同病理类型患者的尿常规及PCT检查结果。结果观察组白细胞计数(6.94±1.05)个/HP、细菌计数(7.75±2.03)×10^5/ml、PCT(2.35±0.45)ng/ml均高于对照组的(60.71±0.22)个/HP、(0.00±0.00)×10^5/ml、(0.20±0.09)ng/ml,差异具有统计学意义(P<0.05)。以细菌培养结果为金标准,白细胞计数、细菌计数、亚硝酸盐的检测准确率分别为68.00%、78.67%以及86.67%。尿常规联合PCT检查对于尿路感染诊断的特异性、敏感性、准确性分别为93.22%、96.70%及95.33%。上尿路感染患者白细胞计数、PCT水平最高,下尿路感染患者次之,慢性肾盂肾炎患者最低;慢性肾盂肾炎患者细菌计数最高,下尿路感染患者次之,上尿路感染患者最低。上尿路感染、下尿路感染、慢性肾盂肾炎患者白细胞计数、细菌计数、PCT水平比较差异均具有统计学意义(P<0.05)。结论在尿路感染鉴别诊断中,尿常规联合PCT检查结果具有重要的参考价值,能够准确诊出尿路感染,并根据各项检测指标水平,对于疾病的病理类型作出判断。

Practical value of urine routine combined with serum procalcitonin test in differential diagnosis of urinary tract infection

Objective To discuss the reference value of urine routine combined with serum procalcitonin(PCT)test in differential diagnosis of urinary tract infection.Methods 150 patients with suspected urinary tract infection(observation group)and 110 healthy subjects(control group)tested at the same time all received routine urine and PCT test successively,as well as urobacterial test,and the urine routine and PCT test results of the two groups were compared.With urobacterial examination as the gold standard,the urine routine and PCT test results of the observation group were analyzed,and the urine routine and PCT test results of different pathological types was compared.Results The white blood cell count(6.94±1.05)pieces/HP,bacterial count(7.75±2.03)×10^5/ml and PCT(2.35±0.45)ng/ml of the observation group were higher than(60.71±0.22)pieces/HP,(0.00±0.00)×10^5/ml and(0.20±0.09)ng/ml of the control group,and the difference was statistically significant(P<0.05).With the results of bacterial culture as the gold standard,the accuracy rates of white blood cell count,bacterial counts,and nitrite detection were 68.00%,78.67%and 86.67%,respectively.The specificity,sensitivity and accuracy of urine routine combined with PCT test for the diagnosis of urinary tract infection were 93.22%,96.70%and 95.33%,respectively.The white blood cell count and PCT level of patients with upper urinary tract infection were the highest,followed by patients with lower urinary tract infection,and the lowest in patients with chronic pyelonephritis;there was statistically significant difference in white blood cell count,bacterial count and PCT levels among patients with upper urinary tract infection,lower urinary tract infection and chronic pyelonephritis(P<0.05).Conclusion In the differential diagnosis of urinary tract infection,the results of urine routine combined with PCT have an important reference value,which can accurately diagnose urinary tract infection,and make judgments on the pathological type of the disease according to the level of various detection indicators.