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缺血性脑血管病病人血浆氧化修饰低密度脂蛋白的检测
引用本文:杜怡峰,张晨,邢昂,徐卫萍. 缺血性脑血管病病人血浆氧化修饰低密度脂蛋白的检测[J]. 青岛大学医学院学报, 2001, 37(1): 39-40
作者姓名:杜怡峰  张晨  邢昂  徐卫萍
作者单位:1. 青岛大学医学院附属医院神经内科
2. 山东省荷泽市中医院
摘    要:①目的 探讨氧化修饰低密度脂蛋白 (OX LDL)与缺血性脑血管病的关系。②方法 应用酶联免疫吸附试验测定了 10 6例缺血性脑血管病病人血浆OX LDL含量。③结果 短暂性脑缺血发作 (TIA)组和脑梗死组血浆OX LDL水平均高于对照组 (F =14.6 7,q =5 .339.85 ,P <0 .0 1) ,且脑梗死急性期较恢复期明显升高(q =4.0 7,P <0 .0 5 )。④结论 血浆OX LDL水平增高可能与缺血性脑血管病的发生发展有密切关系。

关 键 词:脑血管意外 动脉粥样硬化 脂蛋白类 OX-LDL 氯化修饰 脑缺血
文章编号:1001-4047(2001)01-0039-02
修稿时间:1999-12-06

A STUDY ON THE CONCENTRATION OF PLASMA OX-LDL IN PATIENTS WITH ISCHEMIC CEREBROVASCULAR DISEASE
DU Yifeng,ZHANG Chen,XING Ang,et al. A STUDY ON THE CONCENTRATION OF PLASMA OX-LDL IN PATIENTS WITH ISCHEMIC CEREBROVASCULAR DISEASE[J]. Acta Academiae Medicinae Qingdao Universitatis, 2001, 37(1): 39-40
Authors:DU Yifeng  ZHANG Chen  XING Ang  et al
Affiliation:DU Yifeng,ZHANG Chen,XING Ang,et al Department of Neurology,The Affiliated Hospital of Qingdao University Medical College,Qingdao 266003, [
Abstract:Objective To study the relationship between oxidized low density lipoprotein (OX LDL) and ischemic cerebrovascular disease (ICVD). Methods The plasma OX LDL levels were measured in 106 patients with ICVD by using an enzyme linked immunosorbent assay (ELISA). Results The levels of plasma OX LDL in transient ischemic attack (TIA) group and cerebral infarction group were higher than those in the control ( F=14.67,q=5.33-9.85,P <0.01), and the mean values of OX LDL in the acute group were also higher than those in the recovering group ( q=4.07,P <0.05). Conclusion The increase of plasma OX LDL might have remarkable correlation with ICVD. [
Keywords:cerebrovascular disorders  atherosclerosis  lipoproteins   LDL
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