神经外科医院感染相关危险因素临床研究-非条件Logistic模型

目的探讨神经外科医院感染的发病情况及其主要危险因素.方法对2000年1月～2003年1月,收治的2 528例神经外科患者医院感染及其危险因素进行调查分析.结果 161例发生医院感染,感染率为6.37%,感染例次为178例,例次感染率为7.04%;感染部位以下呼吸道、泌尿道和中枢神经系统多见;导致感染的危险因素依次为侵袭性操作、预防性抗菌药物使用、意识障碍程度、H2-受体阻滞剂使用、年龄、住院日等.结论神经外科是医院感染的重点科室,应加强对其医院感染的监测,根据主要危险因素采取有效地预防控制措施.

Nosocomial Infection and Related Risk Factors in Neurosurgery: A Clinical Analysis

OBJECTIVE To explore the distribution and risk factors of nosocomial infection in neurosurgery (department.) METHODS A retrospective study was performed to investigate nosocomial infection in 2 528 patients who were admitted into the department of neurosurgery from Jan 2000 to Jan 2003. RESULTS Totally 161 cases of nosocomial infection were found (the percentage was 6.37%). The infection sites were mainly in lower respiratory tract (31.46%), urinary tract (26.40%) and central nervous system (12.92%) in order. The factors related (nosocomial) infection were invasive manipulation, inappropriate use of broad-spectrum antibiotics, unconsciousness, use of H_2 receptor inhibitors, aged and hospitalization days. CONCLUSIONS Patients in the neurosurgical settings are more likely to develop nosocomial infection. We should strengthen the surveillance and adopt effective measure to prevent nosocomial infection according its mainly risk factors.