急性冠脉综合征患者血红蛋白水平与临床预后关系的探讨

目的：观察不同血红蛋白水平对急性冠脉综合征患者预后的影响。方法：回顾性分析294例急性冠脉综合征患者的临床情况，根据入院血红蛋白水平分成6组，分别统计住院30d内心脏事件发生情况，进行多变量分析各临床参数，估计贫血与心脏事件之间的关系。结果：A、B、C、F组心性死亡发生率为15.62％，9.52％，5．88％，5．26％，高于D、E组（1．85％．1．72％），有统计学差异（P〈0.01）。A、B、C、F组心力衰竭的发生率高于D、E组（12．5％，7．14％，7．84％，5．26％vs1．85％，1.72％），有统计学差异（P〈0．01）。A，B，C，F组心绞痛恶化发生率分别为15．62％，14．28％，7．84％，5.26％，与D、E组（3．70％，3.44％）比较，有统计学差异（P〈0．01）。多因素分析结果提示贫血是急性冠脉综合征独立的预测因素。结论：贫血是急性冠脉综合征患者心脏事件独立的预测因素。

Association of hemoglobin levels with clinical outcomes in acute coronary syndrome

Objective To examine the association between baseline hemoglobin values and major adverse cardiovascular events through 30 days in the patients with acute myocardial infarction.Methods Two hundred ninety-four patients with acute myocardial syndrome were divided into 6 groups according to the hemoglobin.The association was studied between anemia and cardiovascular events by a multivariate analysis of clinical parameters.ResultsWTBZ] The cardiac fatalities were 15.62%,9.52%,5.88% and 5.26% in group A,B,C and F respectively,which were obviously higher than those in group D and E(1.85% and 1.72%)(P<0.01).The incidences of heart failure were 12.5%,7.14%,7.84% and 5.26% in group A,B,C and F,which were higher than those in group D and E(1.85% and 1.72%)(P<0.01).The angina aggravation rate were 15.62%,14.28%,7.84% and 5.26% in group A,B,C and F,which were higher than those in group D and E(3.70% and 3.44%)(P<0.01).The multivariate analysis showed that anemia was an independent predictor of cardiac events.Conclusion Anemia is a power and independent predictor of cardiovascular events in the patients with acute coronary syndrome.