慢性胃炎患者胃内24小时胆汁反流情况研究

目的研究不同类型慢性胃炎患者胃内胆汁反流的情况。方法对43例慢性胃炎患者(慢性浅表性胃炎16例,慢性糜烂性胃炎21例,慢性萎缩性胃炎6例)行胃内24h胆汁监测,获得胆汁反流指标。分析各类患者胆汁反流总时间百分比、反流次数、反流持续5min以上的次数和最长反流时间。结果不同类型慢性胃炎患者胆汁各项监测指标间差别均有显著性意义(P<0·01),慢性萎缩性胃炎患者和慢性糜烂性胃炎患者各项指标明显高于慢性浅表性胃炎患者。结论慢性糜烂性胃炎、慢性萎缩性胃炎的发生与胆汁反流有关。

Study on Bile Reflux for Patients with Chronic Gastritis

Objective To study the bile reflux in patients with different kind of chronic gastritis.Methods The changes of intragastric bile reflux during 24 h were observed by ambulatory bilirubin monitoring techniques in 43 patients(including 16 patients with chronic superficial gastritis,21 with chronic erosive gastritis and 6 with chronic atrophic gastritis).Then analyze the percentage of total time of intragastric bile reflux,the frequency of intragastric bile reflux (>5 min) and the longest persistent time of intragastric bile reflux.Results The total parameteres of bile assessment were significantly different in different kind of chronic gastritis groups (P<0.01),patients in chronic atrophic gastritis group and chronic erosive gastritis group were significantly higher than that in chronic superficial gastritis group(P<0.01).Conclusion Intragastric bile reflux is correlated with chronic erosive gastritis and atrophic gastritis.